RNF20 anticorps
Aperçu rapide pour RNF20 anticorps (ABIN7270071)
Antigène
Voir toutes RNF20 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- RNF20 Rabbit mAb
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human RNF20
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- RNF20 (Ring Finger Protein 20 (RNF20))
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Autre désignation
- RNF20
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Sujet
- The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012],BRE1, BRE1A, hBRE1,Cell Biology & Developmental Biology,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Ubiquitination,Epigenetics & Nuclear Signaling,Histones,Ubiquitin,RNF20
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Poids moléculaire
- 114kDa
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ID gène
- 56254
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UniProt
- Q5VTR2
Antigène
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